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In Retatrutide trials, 91.7% of participants achieved at least 10% body weight reduction at the highest dose

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This helps your body adjust and reduces side effects like nausea and vomiting

Timely data also enables researchers to study new drugs as soon as patients begin taking them

Treatment and monitoring of SAGE-DM Currently, there is no specific evidence-based treatment algorithm for SAGE-DM However, the management of SAGE-DM should be adapted from geriatric diabetes guidelines, considering the underlying aging mechanisms that may affect the response to treatment The following recommendations can thus be viewed as an adaptation of standard care within the SAGE-DM conceptual framework rather than a fully validated treatment pathway Monitoring HbA1c may be unreliable in in the elderly due to comorbidities affecting red blood cell lifespan (e.g., advanced kidney disease, GI bleeding, heart valve defects)